OLGU SUNUMLARI
Tekrarlayan Ä°nmelerin Nedeni Olarak Sistemik Lupus Eritematozusun EÅŸlik EttiÄŸi Antifosfolipid Sendromu: Olgu Sunumu ve Literatür Taraması
Antiphospholipid Syndrome with Systemic Lupus Erythematosus as the Cause of Recurrent Strokes: A Case Report and Literature Review
Received Date : 31 Mar 2023
Accepted Date : 04 Jul 2023
Available Online : 07 Jul 2023
Kerim DEMİRSÖZa, Güldal Funda YÜZER NAKİPOĞLUa, Cemile Sevgi POLATa
aClinic of Physical Medicine and Rehabilitation, Ankara Bilkent City Hospital Ankara, Türkiye
Doi: 10.31609/jpmrs.2023-97114 - Makale Dili: EN
J PMR Sci. 2023;26(3):377-82
ÖZET
Sistemik lupus eritematozus (SLE) ve antifosfolipid sendromu [antiphospholipid
syndrome (APS)] otoimmün hastalıklardır ve artmış serebrovasküler
hastalık riski ile ilişkilidir. APS birincil olabilir, ancak çoğunlukla
SLE ile birlikte görülür. İnme genellikle SLE tanısından sonraki ilk 5 yıl
içinde görülür, ancak nadiren SLE’nin ilk belirtisi olarak ortaya çıkar.
SLE’nin yetersiz teşhisi, tekrarlayan inmelere, morbidite ve mortalitede artışa
neden olur. Bu olgu 64 yaşında, 3 yılda 4 kez inme geçiren ve daha
sonra kliniğimizde APS ve SLE tanısı alan erkek hastadır. Sonuç olarak
inme etiyolojik araştırmalarında, sekonder koruma ile rekürrens riskini azaltmak
için SLE her zaman aklımızda olmalıdır.
Anahtar Kelimeler: Sistemik lupus eritematozus; antifosfolipid sendromu; rekurren inme; yaşlı erkek hasta
ABSTRACT
Systemic lupus erythematosus (SLE) and antiphospholipid
syndrome (APS) are autoimmune diseases and are associated with an increased
risk of cerebrovascular disease. APS can be primary but it is mostly
seen in conjunction with SLE. Stroke is usually seen within the first 5 years
from diagnosis of SLE but it rarely occurs as the initial manifestation of
SLE. Underdiagnosis of SLE causes recurrent strokes, increases in morbidity
and mortality. The present case is a 64 years old male patient who had 4
strokes in 3 years and is subsequently diagnosed with APS and SLE in our
clinic. In conclusion, SLE should always be in our mind during etiologic
investigation of stroke in order to decrease the risk of recurrence by means
of secondary prevention.
Keywords: Systemic lupus erythematosus; antiphospholipid syndrome; recurrent strokes; elderly male patient
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