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ORIJINAL ARAŞTIRMA
Romatoid Artritte Kas Güçsüzlüğü ve Belirleyici Faktörler
Predictive Factors for Muscle Weakness in Rheumatoid Arthritis
Received Date : 11 Nov 2021
Accepted Date : 27 Dec 2021
Available Online : 05 Jan 2022
Özet PDF Benzer Makaleler
Mustafa Erkut ÖNDERa, Ayşegül KILIÇARSLANb, Esra Dilek KESKİNc, Hatice BODURd
aDepartment of Physical Medicine and Rehabilitation, Division of Rheumatology, Aksaray University Training and Research Hospital, Aksaray, Türkiye bClinic of Physical Medicine and Rehabilitation, Maltepe Physical Therapy Center, Ankara, Türkiye cDepartment of Physical Medicine and Rehabilitation, Kırıkkale University Faculty of Medicine, Kırıkkale, Türkiye dClinic of Physical Medicine and Rehabilitation, Ankara City Hospital, Ankara, Türkiye
Doi: 10.31609/jpmrs.2021-87049 - Makale Dili: EN
J PMR Sci. 2022;25(2):248-53
ÖZET
Amaç: Romatoid artritli (RA) hastalarda, kas kuvvetini değerlendirmeyi ve kas kuvvetindeki azalmayı etkileyebilecek yapısal eklem hasarı dâhil çeşitli faktörleri belirlemeyi amaçladık. Bu çalışmada, kas gücü ile yaşam kalitesi ve fonksiyonel yetersizlik arasındaki ilişki incelenmiştir. Gereç ve Yöntemler: Yetmiş beş RA hastası ve 51 kontrol alındı. Demografik özellikler, beden kitle indeksi, bel çevresi, 25 hidroksi vitamin D hastanın hastalık aktivitesinin küresel değerlendirmesi [patient global assessments of disease activity (PGA)] kaydedildi. Hastalık Aktivite Skoru- 28 [Disease Activity Score-28 (DAS28)], Görsel Analog Skala [Visual Analog Scale (VAS)]-ağrı Sağlık Değerlendirme Anketi [Health Assessment Questionnaire (HAQ)] ve Romatoid Artrit Yaşam Kalitesi Anketi [Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL)] hesaplandı. El radyografileri van der Heijde modifiye Sharp skoru [van der Heijde modified Sharp score (vdHSS)] ile değerlendirildi. Jamar dinamometre ile her iki elin kavrama gücü ölçüldü. Bulgular: Demografik özellikler (yaş, cinsiyet) RA hastaları ve kontrol grubu arasında farklı değildi. RA’lı hastaların kavrama gücü (22,79±18,58) kontrol grubundan düşüktü (26,00±11,25; p=0,04). Kavrama gücü ile hastalık süresi, “tender joint count”, VAS-ağrı, PGA, DAS28, HAQ, RAQoL, erozyon ve daralma skoru arasında anlamlı korelasyon vardı (p<0,05). Çok değişkenli analizlerde DAS28 ve erozyon skoru kavrama gücü ile ilişkili bulundu (p<0,05). Sonuç: Bu çalışma, RA’nın kas gücünü azalttığı ve fonksiyonel yetersizliğe ve yaşam kalitesinde bozulmaya neden olduğunu göstermiştir. Eklem aralığı ve hastalık aktivitesi kas gücünü etkileyen ana parametrelerdir.
Anahtar Kelimeler: Kas gücü; beden kitle indeksi; yaşam kalitesi
ABSTRACT
Objective: We aimed to determine muscle strength in patients with rheumatoid arthritis (RA) and several factors including structural joint damage that may affect decrease in muscle strength. The relations between muscle strength and quality of life and functional disability were examined. Material and Methods: Seventy five RA patients and 51 controls were involved. Demographic characteristics, body mass index, waist circumference, 25 hydroxi vitamin D patient global assessments of disease activity (PGA) were documented. Disease Activity Score-28 (DAS28), Visual Analog Scale-Pain (VAS-pain), Health Assessment Questionnaire (HAQ) and the Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL) were calculated. Radiographs of the hands were evaluated by van der Heijde modified Sharp score (vdHSS). Grip strength of both hands measured by Jamar dynamometer. Results: Demographics (age, gender) were not different between RA patients and control group. Grip strength of patients with RA (22.79±18.58) was lower than control group (26.00±11.25, p=0.04). There was significant correlation with grip strength and disease duration, tender joint count, VAS-pain, PGA, DAS28, HAQ, RAQoL, erosion and narrowing score (p<0.05). DAS28 and erosion score were associated with grip strength in multivariate analyses p<0.05). Conclusion: This study showed that RA obtains decreased muscle strength, impaired function and quality of life. Joint space narrowing and disease activity are the main parameters that effect muscle strength.
Keywords: Muscles; body mass index; quality of life
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