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ORIJINAL ARAŞTIRMA

Post-polio Sendromunda Yorgunluk Şiddeti, Duygudurum ve Yaşam Kalitesinin Değerlendirilmesi: Kontrollü Çalışma
Assessment of Fatigue Severity, Mood, and Quality of Life in Post-polio Syndrome: A Controlled Study
Received Date : 05 Jun 2024
Accepted Date : 13 Aug 2024
Available Online : 20 Aug 2024
Doi: 10.31609/jpmrs.2024-104301 - Makale Dili: EN
Turkiye Klinikleri Journal of Physical Medicine and Rehabilitation Sciences. 2024;27(3):208-14
ÖZET
Amaç: Bu çalışma, post-polio sendromu (PPS) hastalarında yorgunluk, yaşam kalitesi, anksiyete ve depresyon düzeyinin değerlendirilmesi ve bulguların sağlıklı gönüllülerle karşılaştırılmasını amaçlamaktadır. Gereç ve Yöntemler: Bu kesitsel kontrollü klinik çalışmaya, 20 PPS’li hasta ve 20 sağlıklı gönüllü dâhil edildi. Yorgunluk şiddeti, Yorgunluk Şiddet Ölçeği [Fatigue Severity Scale (FSS)], yaşam kalitesi Kısa Form-36 [Short Form-36 (SF-36)] ile anksiyete ve depresyon düzeyleri ise Hastane Anksiyete ve Depresyon Ölçeği [Hospital Anxiety and Depression Scale (HADS)] kullanılarak değerlendirildi. Son 1 aydaki ağrı şiddeti Görsel Analog Ölçeği kullanılarak ölçüldü. Bulgular: PPS hastalarında, sağlıklı kontrol grubuna (%45) kıyasla daha yüksek oranda yorgunluk (%70) saptandı. PPS grubunda FSS skorları kontrollere göre anlamlı derecede yüksekti (p: 0,031). HADS depresyon skorları da PPS grubunda kontrollere göre daha yüksek bulundu (p: 0,003). HADS anksiyete skorları, PPS grubunda kontrollere göre daha yüksek olmasına rağmen aradaki fark istatistiksel olarak anlamlı değildi (p>0,05). SF-36 değerlendirmeleri, PPS grubu için tüm yaşam kalitesi alt parametrelerinde anlamlı derecede daha düşük skorlar olduğunu gösterdi (p<0,05). FSS skorları ile yaş (rho: 0,618; p: 0,004) ve polio süresi (rho: 0,606; p: 0,005) arasında pozitif, SF-36 sosyal fonksiyon alt parametresi (rho: -0,475, p: 0,034) arasında negatif korelasyon gözlendi. Sonuç: Bu çalışma, kontrollere kıyasla PPS hastalarında anlamlı derecede yüksek yorgunluk ve depresyon oranlarının olduğunu ve yaşam kalitesinin PPS grubunda daha düşük olduğunu ortaya koymaktadır. PPS’li bireylerde yorgunluk düzeyi, yaş ve polio süresi ile pozitif, sosyal fonksiyon alt parametresi ile negatif korele bulunmuştur.
ABSTRACT
Objective: This study aims to assess fatigue, quality of life, anxiety, and depression in post-polio syndrome (PPS) patients compared to healthy controls. Material and Methods: This cross-sectional study included 20 PPS patients and 20 healthy controls. Fatigue severity was measured utilizing the Fatigue Severity Scale (FSS), while quality of life was evaluated through the Short Form-36 (SF-36). Additionally, depression and anxiety levels were assessed using the Hospital Anxiety and Depression Scale (HADS). Pain intensity over the past month was evaluated using the Visual Analog Scale. Results: PPS patients exhibited higher rates of fatigue (70%) compared to the healthy control group (45%). FSS scores were significantly elevated in the PPS group compared to controls (p:0.031). HADS depression scores were also higher in the PPS group than in controls (p:0.003). While the HADS anxiety scores were elevated in the PPS group compared to controls, the disparity did not reach statistical significance (p>0.05). SF-36 assessments indicated significantly worse scores in all quality of life subparameters for the PPS group (p<0.05). A positive correlation was observed between FSS scores and age (rho: 0.618, p: 0.004) and the duration of polio (rho:0.606, p: 0.005). Additionally, a negative correlation was observed between FSS scores and the SF-36 social functioning subparameter (rho:-0.475, p: 0.034). Conclusion: This study shows significantly higher fatigue and depression rates in PPS patients compared to controls, along with lower quality of life. In PPS patients, fatigue was positively correlated with age and polio duration, and negatively with social functioning subparameter.
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