ORIJINAL ARAŞTIRMA
Post-polio Sendromunda Yorgunluk Şiddeti, Duygudurum ve Yaşam Kalitesinin Değerlendirilmesi: Kontrollü Çalışma
Assessment of Fatigue Severity, Mood, and Quality of Life in Post-polio Syndrome: A Controlled Study
Received Date : 05 Jun 2024
Accepted Date : 13 Aug 2024
Available Online : 20 Aug 2024
Büşra ŞİRİN AHISHAa, Nurdan PAKERb, Nazlı Derya BUĞDAYCIb, Yelda SOLUK ÖZDEMİRb, Nur KESİKTAŞb
aBeylikdüzü State Hospital, Clinic of Physical Medicine and Rehabilitation, İstanbul, Türkiye
bUniversity of Health Sciences İstanbul Physical Therapy and Rehabilitation Training and Research Hospital, Departmant of Physical Medicine and Rehabilitation, İstanbul, Türkiye
Doi: 10.31609/jpmrs.2024-104301 - Makale Dili: EN
Turkiye Klinikleri Journal of Physical Medicine and Rehabilitation Sciences. 2024;27(3):208-14
ÖZET
Amaç: Bu çalışma, post-polio sendromu (PPS) hastalarında
yorgunluk, yaşam kalitesi, anksiyete ve depresyon düzeyinin değerlendirilmesi
ve bulguların sağlıklı gönüllülerle karşılaştırılmasını amaçlamaktadır.
Gereç ve Yöntemler: Bu kesitsel kontrollü klinik
çalışmaya, 20 PPS’li hasta ve 20 sağlıklı gönüllü dâhil edildi. Yorgunluk
şiddeti, Yorgunluk Şiddet Ölçeği [Fatigue Severity Scale (FSS)],
yaşam kalitesi Kısa Form-36 [Short Form-36 (SF-36)] ile anksiyete ve
depresyon düzeyleri ise Hastane Anksiyete ve Depresyon Ölçeği [Hospital
Anxiety and Depression Scale (HADS)] kullanılarak değerlendirildi.
Son 1 aydaki ağrı şiddeti Görsel Analog Ölçeği kullanılarak
ölçüldü. Bulgular: PPS hastalarında, sağlıklı kontrol grubuna (%45) kıyasla
daha yüksek oranda yorgunluk (%70) saptandı. PPS grubunda FSS
skorları kontrollere göre anlamlı derecede yüksekti (p: 0,031). HADS
depresyon skorları da PPS grubunda kontrollere göre daha yüksek bulundu
(p: 0,003). HADS anksiyete skorları, PPS grubunda kontrollere
göre daha yüksek olmasına rağmen aradaki fark istatistiksel olarak anlamlı
değildi (p>0,05). SF-36 değerlendirmeleri, PPS grubu için tüm
yaşam kalitesi alt parametrelerinde anlamlı derecede daha düşük skorlar
olduğunu gösterdi (p<0,05). FSS skorları ile yaş (rho: 0,618; p: 0,004) ve
polio süresi (rho: 0,606; p: 0,005) arasında pozitif, SF-36 sosyal fonksiyon
alt parametresi (rho: -0,475, p: 0,034) arasında negatif korelasyon
gözlendi. Sonuç: Bu çalışma, kontrollere kıyasla PPS hastalarında anlamlı
derecede yüksek yorgunluk ve depresyon oranlarının olduğunu
ve yaşam kalitesinin PPS grubunda daha düşük olduğunu ortaya koymaktadır.
PPS’li bireylerde yorgunluk düzeyi, yaş ve polio süresi ile
pozitif, sosyal fonksiyon alt parametresi ile negatif korele bulunmuştur.
Anahtar Kelimeler: Polio; yorgunluk; depresyon; anksiyete; yaşam kalitesi
ABSTRACT
Objective: This study aims to assess fatigue, quality of
life, anxiety, and depression in post-polio syndrome (PPS) patients
compared to healthy controls. Material and Methods: This cross-sectional
study included 20 PPS patients and 20 healthy controls. Fatigue
severity was measured utilizing the Fatigue Severity Scale (FSS), while
quality of life was evaluated through the Short Form-36 (SF-36). Additionally,
depression and anxiety levels were assessed using the Hospital
Anxiety and Depression Scale (HADS). Pain intensity over the
past month was evaluated using the Visual Analog Scale. Results: PPS
patients exhibited higher rates of fatigue (70%) compared to the healthy
control group (45%). FSS scores were significantly elevated in the PPS
group compared to controls (p:0.031). HADS depression scores were
also higher in the PPS group than in controls (p:0.003). While the
HADS anxiety scores were elevated in the PPS group compared to controls,
the disparity did not reach statistical significance (p>0.05). SF-36
assessments indicated significantly worse scores in all quality of life
subparameters for the PPS group (p<0.05). A positive correlation was
observed between FSS scores and age (rho: 0.618, p: 0.004) and the
duration of polio (rho:0.606, p: 0.005). Additionally, a negative correlation
was observed between FSS scores and the SF-36 social functioning
subparameter (rho:-0.475, p: 0.034). Conclusion: This study
shows significantly higher fatigue and depression rates in PPS patients
compared to controls, along with lower quality of life. In PPS patients,
fatigue was positively correlated with age and polio duration, and negatively
with social functioning subparameter.
Keywords: Polio; fatigue; depression; anxiety; quality of life
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