ORIJINAL ARAŞTIRMA
Fibromiyaljisi Olan ve Olmayan Postmenopozal Osteoporotik Kadın Hastaların D Vitamini Düzeylerinin Karşılaştırılması
Comparison of Vitamin D Levels of Postmenopausal Osteoporotic Female Patients with and Without Fibromyalgia
Received Date : 08 Nov 2023
Accepted Date : 08 Feb 2024
Available Online : 15 Feb 2024
Deniz BULUTa, Nazlı KARAMANa
aEvliya Çelebi Training and Research Hospital, Clinic of Physical Medicine and Rehabilitation, Kütahya, Türkiye
Doi: 10.31609/jpmrs.2023-100230 - Makale Dili: EN
Turkiye Klinikleri Journal of Physical Medicine and Rehabilitation Sciences. 2024;27(2):129-34.
ÖZET
Amaç: Bu araştırmanın amacı, osteoporoz tanısı alan postmenopozal
kadın hastalarda fibromiyalji sıklığı ile D vitamini düzeyleri
arasındaki ilişkinin araştırılmasıdır. Gereç ve Yöntemler: Katılımcıların
öncelikle yaş, cinsiyet, eğitim düzeyi, meslek, medeni durum ve
beden kitle indeksi (BKİ), menopoz ve menarş yaşı, kullandıkları ilaçlar,
kronik hastalıkları, vertebra ve vertebra dışı osteoporotik kırık bilgileri
kaydedildi. Hastaların daha sonra fibromiyalji sendromu “2016
American College of Rheumatology” kriterlerine göre değerlendirilerek,
fibromiyalji sendromu olan ve olmayanlar belirlendi. Tüm hastaların
kan 25(OH) D vitamini düzeyleri dosyalarına kaydedildi.
Bulgular: Çalışmaya katılan 68 postmenopozal osteoporotik kadının
23’ünde (%33,8) fibromiyalji saptandı. Hastaların 40’ında D vitamini
düzeyi 20 ng/mL’nin altında saptandı (%58,8). Fibromiyalji tanısı alan
ve almayanların yaş, boy, kilo, eğitim düzeyi, medeni durum, BKİ, menopoz
ve menarş yaşı veya L1-L4 ve femur toplam kemik mineral yoğunluğu
(KMY) değerlerinde anlamlı farklılık saptanmadı (p>0,05).
Düşük D vitamini düzeyi ile fibromiyalji sıklığı arasında anlamlı ilişki
bulunamadı (p=0,806). Fibromiyalji tanısı alan ve almayanların femur
boynu T skorları ile femur boynu KMY’leri arasında anlamlı fark saptandı.
Femur boynu T skoru değeri fibromiyalji sendromu eşlik eden
hastalarda daha yüksek bulundu. Sonuç: Bu çalışmada, osteoporoz tanılı
kadın hastalarda fibromiyalji görülme sıklığı daha yüksek bulunmasına
rağmen osteoporoz tanılı hastalarda D vitamini düzeyleri ile
fibromiyalji varlığı arasında anlamlı bir ilişki saptanmadı.
Anahtar Kelimeler: Postmenopozal osteoporoz; fibromiyalji; D vitamini; kronik ağrı
ABSTRACT
Objective: To investigate the relationship between the
frequency of fibromyalgia and vitamin D levels in postmenopausal female
patients diagnosed with osteoporosis. Material and Methods:
The participants’ demographic data were first taken, including age, sex,
education level, occupation, marital status and body mass index (BMI),
age of menopause and menarche, drugs used, chronic diseases, and data
on any osteoporotic fractures. The patients were then evaluated according
to the fibromyalgia-syndrome 2016 American College of
Rheumatology criteria, and those with and without fibromyalgia syndrome
were identified. Blood 25(OH) vitamin D levels of all patients
were recorded in their files. Results: Of the 68 women in the study, 23
had fibromyalgia (33.8%). Vitamin D levels were lower than 20 ng/mL
in 40 of the patients (58.8%). No significant differences were noted in
the age, height, weight, education level, marital status, BMI, age of
menopause and menarche, or the total bone mineral density (BMD) values
in L1-L4 and the femurs of those diagnosed and not diagnosed with
fibromyalgia (p>0.05). No significant association was found between
low vitamin D levels and the frequency of fibromyalgia (p=0.806). Significant
differences were noted between the femur neck T-scores and
femur neck BMDs of those diagnosed and not diagnosed with fibromyalgia.
The femoral neck T score was found to be higher in patients
with fibromyalgia. Conclusion: There was a greater prevalance
of fibromyalgia in patients with osteoporosis in the present study, although
no significant association was identified between vitamin D levels
and the presence of fibromyalgia in the patients with osteoporosis.
Keywords: Postmenopausal osteoporosis; fibromyalgia; vitamin D; chronic pain
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